Another day, another grim COVID-19 record.

The U.S. reported 488,000 new COVID infections on Wednesday, according to The New York Times, a pandemic high. The previous record was established the day before. (Monday’s tally was the largest, but included cases from over the weekend.)

The seven-day average of new infections hit 301,000 on Wednesday, also a record.

“In the past week,” writes The Times “more than two million cases have been reported nationally, and 15 states and territories reported more cases than in any other seven-day period.”

“Record caseloads are being reported in a long list of U.S. cities where vaccination rates are relatively high, including New York, Washington, Seattle, San Francisco, Boston, Atlanta and Detroit,” The Times adds, explaining that population density – and the availability of tests – are likely behind the elevated urban numbers.

The increase in cases is largely driven by the omicron variant.

“In a few short weeks, omicron has rapidly increased across the country, and we expect it will continue to circulate in the coming weeks,” Centers for Disease Control and Prevention Director Rochelle Walensky said Wednesday at a White House Covid-19 briefing.

While the omicron variant is clearly more transmissible, evidence is emerging that it is also less severe than previous strains.

Walensky said that hospitalizations are “comparatively low,” even though they’ve ticked up 14% over the last week. Total cases have surged 60% in that same time period.

“All indications point to a lesser severity of omicron versus delta,” Dr. Anthony Fauci, the government’s leading infectious disease expert, said on Wednesday.

But Fauci noted that “we should not become complacent,” because the “extremely high volume” of omicron cases can overwhelm hospitals and push the healthcare system to the breaking point.

Fauci added that “The risk of severe disease from any circulating variant, including Omicron is much, much higher for the unvaccinated.”

According to the CDC, the unvaccinated “are 17 times more likely” to be hospitalized with Covid-19 than the vaccinated.